Allopregnanolone, also known by its chemical name 3α-hydroxy-5α-pregnan-20-one, is a potent endogenous inhibitory pregnane neurosteroid. Synthesized naturally from progesterone, it acts as a high-affinity positive allosteric modulator of the γ-aminobutyric acid type A (GABAA) receptor. Spectrum Chemical provides this non-graded reagent specifically for laboratory research, pharmaceutical development, and industrial applications. It is a critical compound in the study of neuroplasticity, mood disorders, and neuroprotective pathways.
Available in high-purity crystalline form, optimized for consistent results in neurochemical assays and biosynthetic modeling.
Features:
Potent GABA Modulator: As a positive allosteric modulator of GABAA receptors, it is widely utilized in studies regarding the central nervous system's inhibitory signaling
Biochemical Research Ready: Ideal for investigating the "neurosteroid hypothesis" in relation to stress, anxiety, and postpartum neurological shifts
High Purity Standards: Manufactured by Spectrum Chemical to ensure a stable chemical composition and reproducible results across experimental replicates
Stable Intermediate: Useful as a starting material or reference standard in complex organic synthesis and metabolic profiling
Safety & Regulatory Information:
CAUTION! Research Use Only: This product is indicative of a grade suitable for general industrial use or research purposes. It is not suitable for human consumption or therapeutic use.
Personal Protection: Use standard laboratory PPE including nitrile gloves, safety glasses, and a lab coat. Handle in a well-ventilated area to avoid dust inhalation.
Storage: Store in a cool, dry area. Keep the container tightly closed to maintain the integrity of the steroid structure.
Allopregnanolone, also known by its chemical name 3α-hydroxy-5α-pregnan-20-one, is a potent endogenous inhibitory pregnane neurosteroid. Synthesized naturally from progesterone, it acts as a high-affinity positive allosteric modulator of the γ-aminobutyric acid type A (GABAA) receptor. Spectrum Chemical provides this non-graded reagent specifically for laboratory research, pharmaceutical development, and industrial applications. It is a critical compound in the study of neuroplasticity, mood disorders, and neuroprotective pathways.
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Allopregnanolone
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