USDA Heat Inactivated Fetal Bovine Sera

Achieve consistent, high-quality results in your cell culture with Corning USDA Heat Inactivated Fetal Bovine Serum. As a time-tested, universal supplement, this FBS provides the critical compounds your cells need to thrive. Each batch is meticulously processed to deliver the essential hormones, growth factors, vitamins, and minerals that ensure robust cell proliferation and health.

Sera Processing

Using industry leading techniques, blood is aseptically collected at abattoirs, centrifuged to isolate the serum and immediately frozen for testing and further processing. The raw sera is then true pooled and is triple 0.1 micron sterile filtered with a Sterility Assurance Level (SAL) of 10-3. Every lot then must pass USP <71> and EP 2.6.1 sterility testing, growth promotion testing, as well as test negative for mycoplasma and number of industry-monitored viruses. Authenticity of the fetal bovine serum is verified using industry leading measurements of Gamma-Glutamyl Transferase and Corning's high internal standard of ≤ 10 IU/L. Additional testing includes endotoxin, hemoglobin, pH, osmolality, total protein, and a biochemical profile that contains various metals, proteins, hormones and other metabolites.

Origin Statement

Corning's regular FBS is derived from government registered facilities in North, Central, and South America and outside the United States. All fetal bovine serum is derived from fetuses collected from healthy bovine cows and heifers that have passed ante and post mortem inspection and were found free of contagious diseases. The material was exported from the country of origin accompanied with a Veterinarian Health Certificate.

Quality and Regulatory

• ISO 13485 Certified Quality Management System
• Manufacturing in a cGMP compliant facility operating under 21 CFR 820, Quality System Regulation for Medical Device Manufacturers
• Supply chain is certified for traceability by the International Serum Industry Association (ISIA)
• Every lot is country-of-origin verified using chemical fingerprinting by Oritain™
• Validated irradiation protocols
• Certificates of Suitability (CEP) from the European Directorate for the Quality of Medicines (EDQM) for US origin and Australian origin FBS

Features:

• Buffers against pH changes, neutralizes the effects of heavy metal ions, and inhibits proteolytic activity to help achieve reliable data
• Bovine, Bos tauras species
• Validated process used to heat inactivate serum at 56°C ±2°C for 30 minutes via bulk inactivation of the entire lot in the pooling tank or individual bottles in a water bath

Please Note:This product must be stored between -40°C to -10°C. This product is non-returnable. If you have any questions, please contact us immediately.