Ultra-Low Attachment (ULA) Culture Dishes
Manufacturer: Corning Life Sciences
Revolutionize your suspension cultures and 3D cell models with Corning® Ultra-Low Attachment (ULA) Culture Dishes. These dishes feature a unique, covalently bound hydrogel layer that is hydrophilic and neutrally charged. This surface effectively masks the underlying polystyrene, preventing anchorage-dependent cells from attaching and forcing them into a suspended state. This environment is essential for the successful formation of spheroids, embryoid bodies, and mammospheres.
Description
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Beyond simply inhibiting attachment, the ULA surface is engineered to minimize protein adsorption, enzyme activation, and cellular activation. This ensures that your cells remain in a controlled, "neutral" state, making these dishes the premier choice for studying stem cells, cancer cell colonies, and primary cultures that are sensitive to surface-induced signaling.
Features:
- True Suspension Culture: The hydrogel surface creates a biologically inert environment where cells cannot latch onto the plastic
- Optimized for 3D Spheroids: Promotes the self-assembly of cells into uniform 3D structures for more accurate in vivo modeling
- Superior Clarity: Manufactured from optically-clear virgin polystyrene, allowing for high-quality microscopic observation of floating clusters
- Advanced Gas Exchange: Integrated vents in the lid ensure consistent CO2 and O2 exchange for healthy metabolic activity
- Safety & Purity: Sterilized by gamma radiation, certified nonpyrogenic, and non-cytotoxic
- Ease of Use: Designed with stacking beads for stable handling and efficient use of incubator space.
Comparison: Standard vs. Ultra-Low Attachment
- Standard TC-Treated: Charged surface designed to pull proteins down, allowing cells to anchor and spread (monolayer)
- Ultra-Low Attachment: Hydrophilic hydrogel "hides" the surface from cells, keeping them in a natural rounded state or promoting 3D aggregation
Primary Applications:
- Cancer Research: Colony formation assays and tumor spheroid studies
- Stem Cell Research: Culturing embryoid bodies (EBs) without premature differentiation
- Cell Therapy: Maintenance of primary cells in a non-activated state
- Neurology: Formation of neurospheres for developmental studies
| SKU | Sterility | Bottom Style | Color | Material | Type | Volume | Height | Diameter |
|---|---|---|---|---|---|---|---|---|
| 3261 | Sterile | Flat | Clear | Polystyrene | Ultra-Low Attachment | 4.2 mL - 6.3 mL | 5 mm (approx.) | 52.1 mm (approx.) |
| 4615 | Sterile | Flat | Clear | Polystyrene | Ultra-Low Attachment | 11 mL - 16.5 mL | 20 mm (approx.) | 83.8 mm (approx.) |
| SKU | Dimensions | Capacity |
|---|---|---|
| 3261 | 15 mm x 52.1 mm | 100 mm |
| 4615 | 20 mm x 83.8 mm | 100 mm |
Revolutionize your suspension cultures and 3D cell models with Corning® Ultra-Low Attachment (ULA) Culture Dishes. These dishes feature a unique, covalently bound hydrogel layer that is hydrophilic and neutrally charged. This surface effectively masks the underlying polystyrene, preventing anchorage-dependent cells from attaching and forcing them into a suspended state. This environment is essential for the successful formation of spheroids, embryoid bodies, and mammospheres.
Starting at $333.70
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